1/31/2024 0 Comments Download large earthworm![]() Meanwhile, single-cell RNA-sequencing provides insight into the regenerative process at a cellular level and finds that the largest proportion of cells present during regeneration are stem cells. Furthermore, early growth response genes related to regeneration are transcriptionally activated in both the earthworm and planarian. Temporal gene expression trajectories identify transcriptional regulatory factors that are potentially crucial for initiating cell proliferation and differentiation during regeneration. We observe expansion of LINE2 transposable elements and gene families functionally related to regeneration (for example, EGFR, epidermal growth factor receptor) particularly for genes exhibiting differential expression during earthworm regeneration. Here we report chromosome-level genome, large-scale transcriptome and single-cell RNA-sequencing data during earthworm ( Eisenia andrei) regeneration. ![]() However, many aspects of its regeneration in nature remain elusive. The earthworm is particularly fascinating to biologists because of its strong regenerative capacity.
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